Aug 06 / 2021
Modafinil dosage administration
How much should I take?
Those patients who suffer from narcolepsy and OSA, it is recommended to have 200 mg of Generic Modafinil in the early morning. Those who faced with work shifts, it is better to have the same dose 1 hour before this shift starts. It is suggested to prescribe lower doses of the drug for those people who are elderly or may have some hepatic impairment. Those who suffer from severe hepatic impairment are usually prescribed 100 mg of the medication per day. Modafinil is found to be absorbed and metabolized primarily by your liver.
The results of some studies show that the most frequent side effects which occurred during the treatment with Modafinil were nausea, insomnia, headaches, diarrhea, dyspepsia and dizziness. The most commonly reported was headache. In order to avoid such a symptom it is recommended to drink much water while having the treatment with the medication. It is already known that Modafinil doesn’t have those euphorigenic characteristics and its potential for abuse is really minimal.
Modafinil for MDD.
There was evidence of Modafinil usage in treating Major Depressive Disorder (MDD). It is often possible to see such concomitant symptoms as fatigue and excessive sleep. Those patients who faced with such depressive symptoms can get much benefit from the therapy with Modafinil due to its stimulating characteristics. Such traditional stimulant as methylphenidate is used to improve depressive neurovegetative symptoms. In comparison with it Modafinil has a number of additional benefits. They are the following:
• Less interactions with drugs
• Reduced adverse CNS effects
• Little risk for abuse and dependence
Two placebo-controlled, double-blind studies estimated adjunctive Modafinil in the treatment of patients who faced with MDD which didn’t remit and who somehow responded onto selective serotonin reuptake inhibitor therapy. In one study the medication gave a considerable reduction in Epworth Sleepiness Scale scores after 1 week and after 2 week showed changes on Fatigue Severity Scale. Generally, the results of modafinil groups and placebo groups were not significantly different.
Another 6 week investigation with 25 patients who suffered from depression showed that Modafinil considerably improved their symptoms. Many of them were suggested to order Modafinil to continue treatment with it. This off-label usage of the medication is not officially approved by FDA but it is often used among a majority of people. Currently a number of investigations are being conducted to find out more about Modafinil influence on MDD.
In spite of all things, many people buy Modafinil and use it without any problems. It has become a very popular drug at each home in many countries already. It is believe that soon it will become one of the most popular drugs on the whole world.