Provigil clinical studies
How does Provigil help for Narcolepsy?
One US 9 week study with a multi-center, parallel group, placebo controlled double-blind investigation showed the efficacy of Generic Provigil in enhancing and improving feeling of wakefulness in grown-up patients who suffered from excessive sleep which was caused by narcolepsy. 558 people took part in the experiment. They received Provigil 200 and 400 mg per day, some got a placebo.
The criteria for being ill with narcolepsy included the following symptoms: recurrent lapses and naps during a day, which lasted during the period of 3 months, abrupt bilateral loss of postural muscle tone which is associated with intense emotions, excessive sleepiness and abrupt weakness of muscles, including sleep paralysis, automatic behaviors, hypnagogic hallucinations, disrupted major sleep episodes and even polysomnography. In order to participate in the study it was required to have the excessive daytime sleepiness documented officially with the help of Multiple Sleep Latency Test.
Those patients who got the treatment with Provigil were noticed to have significant enhanced ability to stay awake on the MWT with each dose in comparison with those who got only placebo. Those people who were treated with Provigil showed much improvement in the general overall health condition. The use of Provigil didn’t affect the nighttime sleep. Those who received the most of benefits from the drug were recommended to order Provigil and continue treatment with it in order to experience more positive effects.
Provigil for OSA.
After 2 multicenter, clinical, placebo-controlled studies it was found out that Provigil is really very effective in treating such a condition as OSA. The symptoms included too much sleep, insomnia, frequents episodes of impaired breathing while sleeping, long snoring, dry mouth and morning headaches. To participate in these studies it was important to have excessive sleepiness equal or more than 10 according to Epworth Sleepiness Scale (ESS), not taking into consideration the treatment with CPAP. It was also significant to have the documented evidence of the effectiveness of Continuous Positive Airway Pressure.
A significant amount of people who got the treatment with Provigil showed much improvement in the general health condition. It was also suggested to buy Provigil for those patients who got significant changes in the functioning of the cognition. The doses of 200 and 400 mg a day gave significant positive changes on the MWT. There were not noticed any effects of Provigil on night sleep patterns. It is proved that Provigil is really very good and well-tolerated when is taken in a right way without any violations, according to all the advice and recommendations of the doctor. If you are not sure in something, it is better to contact your physician once more.
Provigil is found to be effective in improving the symptoms of narcolepsy, OSA and SWSD. It is investigated much to reveal it additional properties.